Integrated genomic and transcriptomic analyses of long non-coding RNAs in dog as a model of human melanoma

Recent efforts have extended the dog genome annotation with the discovery of thousands of long non coding RNAs (lncRNAs) using the machine-learning based tool FEELnc [1]. Although lncRNAs have been shown to play important roles in many biological processes, and particularly in cancers [2], it remains challenging to assign functions and classify lncRNAs in order Read more about Integrated genomic and transcriptomic analyses of long non-coding RNAs in dog as a model of human melanoma[…]

Swedish actions to “handle” Brachycephalic Obstructive Airway Syndrome (BOAS) related health issues

The poster is reviewing Swedish actions to improve health issues related to Brachycephalic Obstructive Airway Syndrome (BOAS) and handling the increased attention and awareness of the syndrome. These actions are forming of working groups composed of various stakeholders, arranging conferences and production of educational material for breeders, judges and veterinarians (a,b). reviewing the epidemiology of Read more about Swedish actions to “handle” Brachycephalic Obstructive Airway Syndrome (BOAS) related health issues[…]

Population structure of Leonberger dogs

The Leonberger is a giant dog breed formed in the 1850s in Germany. This breed appears to have higher predisposition to neurodegenerative disorders and osteosarcoma than other breeds. Every second polyneuropathy-diagnosed Leonberger can be explained by dominantly inherited ARHGEF10 or GJA9 variants and a recently described recessive NAPEPLD variant identifies a juvenile-onset leukoencephalomyelopathy. Breeders also Read more about Population structure of Leonberger dogs[…]

Genetic and environmental risk factors for canine atopic dermatitis evaluated in a population of owned Labrador and Golden retrievers

Canine atopic dermatitis (cAD) is a common clinical syndrome with no definitive diagnostic tests, which causes marked morbidity and has a high economic impact. Past efforts at evaluating the epidemiology and genetics of cAD have relied upon extensive clinical examination to identify subjects, which has limited sample sizes. In this study, we created a novel Read more about Genetic and environmental risk factors for canine atopic dermatitis evaluated in a population of owned Labrador and Golden retrievers[…]